Endocrine disorders encompass a broad category of diseases that occur when the endocrine system, the network of glands that produce, store, and release hormones into the bloodstream, does not function properly. These hormones are vital for controlling a variety of bodily processes, including metabolism, mood, sleep, growth and development, tissue function, sexual function, and reproduction. A disturbance in the hormone balance might result in serious health problems.

Boy suffering from Endocrine disorders

Common Causes of Endocrine Disorders

Endocrine disorders are often caused by various factors, including genetic mutations, diseases, infections, changes in the body's immune system, or damage to an endocrine gland. Some common conditions, like diabetes, occur when glands produce too much or too little of a hormone, known as hyperfunction and hypofunction. Other disorders, such as thyroid diseases, can arise from structural problems in the glands, including growths or tumours.

Symptoms to Look Out For

The symptoms of endocrine problems might vary depending on which hormone is implicated, but they frequently include changes in blood pressure or heart rate, exhaustion, increased thirst or urination, muscle weakness, mood swings, blurred vision, changes in appetite, and abnormalities in digestion. For instance, signs of hypothyroidism, or underactive thyroid, can include weight gain, lethargy, and cold intolerance. In contrast, an overactive thyroid (hyperthyroidism) might result in weight loss, increased heart rate, and anxiety.

Treatments Available

The treatment for endocrine disorders depends on the specific disease and the underlying cause but typically focuses on restoring hormone balance. Common treatments include:

Monitoring and Management

Effective management of endocrine disorders often requires a comprehensive approach, including regular monitoring of hormone levels, adherence to treatment plans, and adjustments to therapies as needed. Untreated endocrine abnormalities can result in major health complications because the endocrine system is essential to general health. Therefore, early detection and treatment are crucial.

In summary, endocrine disorders are a group of diseases resulting from the dysfunction of the glands in the endocrine system. They can have a variety of causes and symptoms, which can make diagnosis difficult at times. However, with proper treatment and management, many people with endocrine disorders can lead healthy, normal lives.

Contact Us

If you think that your child may be suffering from an endocrine related disorder, please contact Paediatric Diagnostics today to arrange an initial consultation.


Cows' milk protein allergy (CMPA) can present with a range of symptoms in children, affecting the skin , digestive, and respiratory systems. Look out for signs such as abdominal pain, vomiting, diarrhoea, eczema, blood or mucous in stools, constipation, severe gastro-oesophageal reflux, wheezing, and excessive fussiness after feeding.

Navigating Cows' Milk Protein Allergy in Children: A Parent's Essential Guide


CMPA occurs when a child's immune system reacts adversely to proteins found in cow's milk. The two main proteins responsible are casein and whey. The immune response triggers symptoms ranging from mild discomfort to severe reactions, making it crucial for parents to be aware of potential allergens in their child's diet.


The primary treatment for CMPA involves eliminating all sources of cows' milk protein from the child's diet. This includes breastfeeding mothers avoiding dairy or switching to hypoallergenic formulas. In severe cases, healthcare providers may prescribe specialised hypoallergenic formulas to ensure the child receives adequate nutrition.

When to See a Doctor:

If you notice persistent symptoms in your child that may be indicative of CMPA, it's important to consult a healthcare professional. Early diagnosis and management can significantly improve the child's quality of life. Immediate medical attention is crucial if there are severe symptoms like difficulty breathing or anaphylaxis.


Confirmation of CMPA often involves diagnostic investigations. These may include skin prick tests, blood tests measuring specific antibodies, or an oral food challenge under medical supervision. These tests help healthcare providers determine the severity of the allergy and guide appropriate treatment.


Preventing CMPA largely revolves around early detection and careful dietary management. If there is a family history of allergies, especially to cows' milk, it's advisable to monitor your child closely for any signs of allergic reactions. When introducing solids, gradually incorporate new foods, and be vigilant for any adverse reactions. By understanding the symptoms, causes, and preventive measures associated with cows' milk protein allergy, parents can actively contribute to their child's well-being.

Regular communication with healthcare providers ensures a collaborative approach in managing CMPA and providing the best possible care for your child.

Contact Paediatric Diagnostics today.

A recent article by the Standard newspaper explained how Professor CK Sinha, Consultant Paediatric General and Urology Surgeon, and his team helped to save the life of a premature baby who was expected to die a few hours after being born when surgeons discovered she had a dead bowel.


Regarding the surgery, Professor Sinha said, “The surgery was a huge success, and we were so excited to see it happen, but it was also a challenging journey.

“We kept ourselves positive, and a huge credit needs to go to Connie’s parents, who were so supportive throughout. It was a whole team effort, and everyone was there to support Connie and her parents throughout their journey.”

Read the full article here: Doctors save life of baby with ‘miracle’ rare surgery at St George’s Hospital in south London.

Professor CK Sinha has over 25 years’ experience in paediatric surgery and paediatric urology, and is part of the team at Paediatric Diagnostics.

He has authored or contributed to over 115 publications, 15 books, and 50 national and international presentations. One of his most popular books is ‘Handbook of Paediatric Surgery’, published by Springer London – New York.

He is also the Clinical Governance Lead at St George’s Medical School and is actively involved in training the next generation.

To learn more about Professor CK Sinha, and the rest of our amazing team at Paediatric Diagnostics, please click here.

Our Medical Consultants and Surgeons are registered with the GMC (General Medical Council) and are regulated by the Care Quality Commission (CQC). The CQC is an independent regulator for health and social care in England. 
© All rights reserved